"EZH2" Related Products

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Recombinant Human EZH2 Complex protein, His/Flag-tagged

Cat.No. : EZH2-174H
Product Overview : Mutant version of EZH2 5-member complex, but with a Ala-to-Gly mutation on a.a. 682 of the EZH2 protein. Complex of human EZH2 (GenBank Accession No. NM_004456), a.a. 2-end, A682G, with N-terminal His-tag, MW= 86 kDa, human EED (NM_003797), a.a. 2-end with N-terminal FLAG-tag, MW= 51 kDa, human SUZ12 (NM_015355), a.a. 2-end with N-terminal His-tag, MW = 87 kDa, Human AEBP2 (NM_153207), a.a. 2-end with N-terminal His-tag, MW= 53 kDa, and human RbAp48 (NM_005610), a.a. 2-end with N-terminal His-tag, MW = 48 kDa, co-expressed in a baculovirus expression system.
Source : Insect cells
Species : Human
Tag : His/Flag
Form : 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20 mM imidazole, and 20% glycerol.
Molecular Mass : 325 kDa (complex)
Protein length : 2–end (all components)
Purity : ≥ 82%
Applications : Useful for Western blot analysis and to investigate protein-protein interactions in the EZH2 complex.
Storage : >6 months at -80 centigrade. Avoid freeze/thaw cycles
Concentration : 0.105 mg/ml
Gene Name : EZH2 enhancer of zeste homolog 2 (Drosophila) [ Homo sapiens ]
Official Symbol : EZH2
Synonyms : EZH2; enhancer of zeste homolog 2 (Drosophila); enhancer of zeste (Drosophila) homolog 2; histone-lysine N-methyltransferase EZH2; ENX 1; EZH1; KMT6; KMT6A; lysine N-methyltransferase 6; ENX1; WVS2; ENX-1; MGC9169;
Gene ID : 2146
mRNA Refseq : NM_004456
Protein Refseq : NP_004447
MIM : 601573
UniProt ID : Q15910
Chromosome Location : 7q35-q36
Function : DNA binding; histone methyltransferase activity; histone-lysine N-methyltransferase activity; methyltransferase activity; protein binding; transferase activity;

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