Recombinant Human EZH2 Protein, GST-tagged

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Recombinant Human EZH2 Protein, GST-tagged

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Cat.No. : EZH2-285H
Product Overview : Recombinant full-length human EZH2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : EZH2 (enhancer of zeste homolog 2) belongs to the polycomb group (PcG) protein and acts as the catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of target genes. EZH2 expression is associated with proliferating tissues and shares an overlapping set of target genes with EZH1. Compared to PRC2-EZH1, PRC2-EZH2 exhibits higher levels of histone methyltransferase (HKMT) activity.
Source : Insect cell
Species : Human
Tag : GST
Form : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Mass : ~130 kDa
Purity : > 85%
Storage : Store product at -70 centigrade.
Concentration : 0.05ug/uL
Gene Name : EZH2 enhancer of zeste homolog 2 (Drosophila) [ Homo sapiens ]
Official Symbol : EZH2
Synonyms : EZH2; enhancer of zeste homolog 2 (Drosophila); enhancer of zeste (Drosophila) homolog 2; histone-lysine N-methyltransferase EZH2; ENX 1; EZH1; KMT6; KMT6A; lysine N-methyltransferase 6; ENX1; WVS2; ENX-1; MGC9169
Gene ID : 2146
mRNA Refseq : NM_001203247
Protein Refseq : NP_001190176
MIM : 601573
UniProt ID : Q15910

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