Recombinant Human FANCB Protein, GST-tagged

• Cat.No.: FANCB-3826H
• Product Overview: Human FANCB full-length ORF ( NP_001018123.1, 1 a.a. - 859 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the Fanconi anemia complementation group B. This protein is assembled into a nucleoprotein complex that is involved in the repair of DNA lesions. Mutations in this gene can cause chromosome instability and VACTERL syndrome with hydrocephalus. [provided by RefSeq, Apr 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 124.1 kDa
• AA Sequence: MTSKQAMSSNEQERLLCYNGEVLVF QLSKGNFADKEPTKTPILHVRRMVF DRGTKVFVQKSTGFFTIKEENSHLK IMCCNCVSDFRTGINLPYIVIEKNK KNNVFEYFLLILHSTNKFEMRLSFK LGYEMKDGLRVLNGPLILWRHVKAF FFISSQTGKVVSVSGNFSSIQWAGE IENLGMVLLGLKECCLSEEECTQEP SKSDYAIWNTKFCVYSLESQEVLSD IYIIPPAYSSVVTYVHICATEIIKN QLRISLIALTRKNQLISFQNGTPKN VCQLPFGDPCAVQLMDSGGGNLFFV VSFISNNACAVWKESFQVAAKWEKL SLVLIDDFIGSGTEQVLLLFKDSLN SDCLTSFKITDLGKINYSSEPSDCN EDDLFEDKQENRYLVVPPLETGLKV CFSSFRELRQHLLLKEKIISKSYKA LINLVQGKDDNTSSAEEKECLVPLC GEEENSVHILDEKLSDNFQDSEQLV EKIWYRVIDDSLVVGVKTTSSLKLS LNDVTLSLLMDQAHDSRFRLLKCQN RVIKLSTNPFPAPYLMPCEIGLEAK RVTLTPDSKKEESFVCEHPSKKECV QIITAVTSLSPLLTFSKFCCTVLLQ IMERESGNCPKDRYVVCGRVFLSLE DLSTGKYLLTFPKKKPIEHMEDLFA LLAAFHKSCFQITSPGYALNSMKVW LLEHMKCEIIKEFPEVYFCERPGSF YGTLFTWKQRTPFEGILIIYSRNQT VMFQCLHNLIRILPINCFLKNLKSG SENFLIDNMAFTLEKELVTLSSLSS AIAKHESNFMQRCEVSKGKSSVVAA ALSDRRENIHPYRKELQREKKKMLQ TNLKVSGALYREITLKVAEVQLKSD FAAQKLSNL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FANCB Fanconi anemia, complementation group B [ Homo sapiens ]
• Official Symbol: FANCB
• Synonyms: FANCB; Fanconi anemia, complementation group B; Fanconi anemia group B protein; FAAP95; FAB; FLJ34064; Fanconi anemia-associated polypeptide of 95 kDa; FA2; FACB; FAAP90
• Gene ID: 2187
• mRNA Refseq: NM_001018113
• Protein Refseq: NP_001018123
• MIM: 300515
• UniProt ID: Q8NB91