Recombinant Human FANCC Protein (1-558 aa), His-SUMO-tagged

• Cat.No.: FANCC-497H
• Product Overview: Recombinant Human FANCC Protein (1-558 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Full Length.

Specification

• Description: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
• Source: E. coli
• Species: Human
• Tag: His-SUMO
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 79.4 kDa
• Protein length: 1-558 aa
• AA Sequence: MAQDSVDLSCDYQFWMQKLSVWDQA STLETQQDTCLHVAQFQEFLRKMYE ALKEMDSNTVIERFPTIGQLLAKAC WNPFILAYDESQKILIWCLCCLINK EPQNSGQSKLNSWIQGVLSHILSAL RFDKEVALFTQGLGYAPIDYYPGLL KNMVLSLASELRENHLNGFNTQRRM APERVASLSRVCVPLITLTDVDPLV EALLICHGREPQEILQPEFFEAVNE AILLKKISLPMSAVVCLWLRHLPSL EKAMLHLFEKLISSERNCLRRIECF IKDSSLPQAACHPAIFRVVDEMFRC ALLETDGALEIIATIQVFTQCFVEA LEKASKQLRFALKTYFPYTSPSLAM VLLQDPQDIPRGHWLQTLKHISELL REAVEDQTHGSCGGPFESWFLFIHF GGWAEMVAEQLLMSAAEPPTALLWL LAFYYGPRDGRQQRAQTMVQVKAVL GHLLAMSRSSSLSAQDLQTVAGQGT DTDLRAPAQQLIRHLLLNFLLWAPG GHTIAWDVITLMAHTAEITHEIIGF LDQTLYRWNRLGIESPRSEKLAREL LKELRTQV
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: FANCC Fanconi anemia, complementation group C [ Homo sapiens ]
• Official Symbol: FANCC
• Synonyms: FANCC; FACC; FA3; FAC; FLJ14675
• Gene ID: 2176
• mRNA Refseq: NM_000136
• Protein Refseq: NP_000127
• MIM: 613899
• UniProt ID: Q00597