FAP-28897TH
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant fragment corresponding to amino acids 29-760 of Human Fibroblast activation protein, alpha with C terminal His tag expressed in a Baculovirus infected Sf9 cell expression system, 85.5 kDa.
Description :
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.
Conjugation :
HIS
Tissue specificity :
Fibroblast specific.
Biological activity :
Specific Activity: 10.2 pmol/min/μg.Assay Condition: 50 mM Tris-HCl (pH7.5), 10 mM MgCl2, 1 mM MnCl2, 5μM substrate (A-P-AMC), room temperature.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.