| Description : |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3' end. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
54.6 kDa |
| AA Sequence : |
MAAMETETAPLTLESLPTDPLLLIL SFLDYRDLINCCYVSRRLSQLSSHD PLWRRHCKKYWLISEEEKTQKNQCW KSLFIDTYSDVGRYIDHYAAIKKAW DDLKKYLEPRCPRMVLSLKEGAREE DLDAVEAQIGCKLPDDYRCSYRIHN GQKLVVPGLLGSMALSNHYRSEDLL DVDTAAGGFQQRQGLKYCLPLTFCI HTGLSQYIAVEAAEGRNKNEVFYQC PDQMARNPAAIDMFIIGATFTDWFT SYVKNVVSGGFPIIRDQIFRYVHDP ECVATTGDITVSVSTSFLPELSSVH PPHYFFTYRIRIEMSKDALPEKACQ LDSRYWRITNAKGDVEEVQGPGVVG EFPIISPGRVYEYTSCTTFSTTSGY MEGYYTFHFLYFKDKIFNVAIPRFH MACPTFRVSIARLEMGPDEYEEMEE EEEEEEEEDEDDDSADMDESDEDDE EERRRRVFDVPIRRRRCSRLFTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
