Recombinant Human FBXO3, His-tagged

• Cat.No.: FBXO3-12794H
• Product Overview: Recombinant Human FBXO3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 124-471a.a.
• Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3 end.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FBXO3 F-box protein 3 [ Homo sapiens ]
• Official Symbol: FBXO3
• Synonyms: FBXO3; F-box protein 3; F box only protein 3; F-box only protein 3; FBA; FBX3; F-box protein FBX3; DKFZp564B092
• Gene ID: 26273
• mRNA Refseq: NM_012175
• Protein Refseq: NP_036307
• MIM: 609089
• UniProt ID: Q9UK99
• Chromosome Location: 11p13
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem
• Function: ubiquitin-protein ligase activity