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Recombinant Human FBXO8 Protein, GST-tagged

Cat.No. : FBXO8-3962H
Product Overview : Human FBXO8 full-length ORF ( AAH14679, 1 a.a. - 319 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 60.83 kDa
AA Sequence : MGQGLWRVVRNQQLQQEGYSEQGYL TREQSRRMAASNISNTNHRKQVQGG IDIYHLLKARKSKEQEGFINLEVLP PELSFTILSYLNATDLCLASCVWQD LANDELLWQGLCKSTWGHCSIYNKN PPLGFSFRKLYMQLDEGSLTFNANP DEGVNYFMSKGILDDSPKEIAKFIF CTRTLNWKKLRIYLDERRDVLDDLV TLHNFRNQFLPNALREFFRHIHAPE ERGEYLETLITKFSHRFCACNPDLM RELGLSPDAVYVLCYSLILLSIDLT SPHVKNKMSKREFIRNTRRAAQNIS EDFVGHLYDNIYLIGHVAA
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : FBXO8 F-box protein 8 [ Homo sapiens ]
Official Symbol : FBXO8
Synonyms : FBXO8; F-box protein 8; F box only protein 8; F-box only protein 8; FBS; FBX8; F-box protein Fbx8; F-box/SEC7 protein FBS; DC10;
Gene ID : 26269
mRNA Refseq : NM_012180
Protein Refseq : NP_036312
MIM : 605649
UniProt ID : Q9NRD0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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