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Recombinant Human FBXW8 Protein, GST-tagged

Cat.No. : FBXW8-3977H
Product Overview : Human FBXW8 partial ORF ( NP_699179, 499 a.a. - 598 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.74 kDa
AA Sequence : VWDYRMNQKLWEVYSGHPVQHISFS SHSLITANVPYQTVMRNADLDSFTT HRRHRGLIRAYEFAVDQLAFQSPLP VCRSSCDAMATHYYDLALAFPYNHV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : FBXW8 F-box and WD repeat domain containing 8 [ Homo sapiens ]
Official Symbol : FBXW8
Synonyms : FBXW8; F-box and WD repeat domain containing 8; F box and WD 40 domain protein 8 , F box only protein 29 , FBXO29; F-box/WD repeat-containing protein 8; FBW6; FBW8; FBX29; F-box only protein 29; F-box and WD-40 domain protein 8; F-box and WD-40 domain-containing protein 8; FBXW6; FBXO29; MGC33534;
Gene ID : 26259
mRNA Refseq : NM_012174
Protein Refseq : NP_036306
MIM : 609073
UniProt ID : Q8N3Y1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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