Recombinant Human FBXW8 Protein, GST-tagged
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Cat.No. : | FBXW8-3977H |
Product Overview : | Human FBXW8 partial ORF ( NP_699179, 499 a.a. - 598 a.a.) recombinant protein with GST-tag at N-terminal. |
Description : | This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.74 kDa |
AA Sequence : | VWDYRMNQKL WEVYSGHPVQ HISFSSHSLI TANVPYQTVM RNADLDSFTT HRRHRGLIRA YEFAVDQLAF QSPLPVCRSS CDAMATHYYD LALAFPYNHV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Quality Control Testing : |
![]() 12.5% SDS-PAGE Stained with Coomassie Blue. |
Gene Name : | FBXW8 F-box and WD repeat domain containing 8 [ Homo sapiens ] |
Official Symbol : | FBXW8 |
Synonyms : | FBXW8; F-box and WD repeat domain containing 8; F box and WD 40 domain protein 8 , F box only protein 29 , FBXO29; F-box/WD repeat-containing protein 8; FBW6; FBW8; FBX29; F-box only protein 29; F-box and WD-40 domain protein 8; F-box and WD-40 domain-containing protein 8; FBXW6; FBXO29; MGC33534; |
Gene ID : | 26259 |
mRNA Refseq : | NM_012174 |
Protein Refseq : | NP_036306 |
MIM : | 609073 |
UniProt ID : | Q8N3Y1 |
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