Recombinant Human FCAR Protein, GST-tagged

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Recombinant Human FCAR Protein, GST-tagged

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Cat.No. : FCAR-3983H
Product Overview : Human FCAR partial ORF ( AAH27953, 24 a.a. - 133 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 37.84 kDa
AA Sequence : GDFPMPFISA KSSPVIPLDG SVKIQCQAIR EAYLTQLMII KNSTYREIGR RLKFWNETDP EFVIDHMDAN KAGRYQCQYR IGHYRFRYSD TLELVVTGLY GKPFLSADRG
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : FCAR Fc fragment of IgA, receptor for [ Homo sapiens ]
Official Symbol : FCAR
Synonyms : FCAR; Fc fragment of IgA, receptor for; immunoglobulin alpha Fc receptor; CD89; IgA Fc receptor; Fc alpha receptor;
Gene ID : 2204
mRNA Refseq : NM_002000
Protein Refseq : NP_001991
MIM : 147045
UniProt ID : P24071

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