Recombinant Human FCAR Protein, His-tagged
Cat.No. : | FCAR-213H |
Product Overview : | Recombinant Human FCAR(22-227aa) fused with His tag at C-terminal was expressed in Insect cells. |
- Specification
- Gene Information
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Description : | FCAR, also known as immunoglobulin alpha Fc receptor isoform, is a member of the multichain immune recognition receptor family which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. It plays a role in both pro- and anti-inflammatory responses depending on the state of IgA bound. It is also an important Fc receptor for neutrophil killing of tumor cells. When FCAR expressing neutrophils come into contact with IgA-opsonized tumor cells, the neutrophils not only perform antibody-dependent cell-mediated cytotoxicity, but also release the cytokines TNF-alpha and IL-1beta which cause increased neutrophil migration to the site. |
Source : | Insect cells |
Species : | Human |
Tag : | His |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Molecular Mass : | 24.5kDa (215aa) 28-40kDa (SDS-PAGE under reducing conditions) |
Protein length : | 22-227aa |
AA Sequence : | ADPQEGDFPM PFISAKSSPV IPLDGSVKIQ CQAIREAYLT QLMIIKNSTY REIGRRLKFW NETDPEFVID HMDANKAGRY QCQYRIGHYR FRYSDTLELV VTGLYGKPFL SADRGLVLMP GENISLTCSS AHIPFDRFSL AKEGELSLPQ HQSGEHPANF SLGPVDLNVS GIYRCYGWYN RSPYLWSFPS NALELVVTDS IHQDYTTQNH HHHHH |
Purity : | > 85% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25mg/ml (determined by Absorbance at 280nm) |
Gene Name : | FCAR Fc fragment of IgA, receptor for [ Homo sapiens ] |
Official Symbol : | FCAR |
Synonyms : | FCAR; Fc fragment of IgA, receptor for; immunoglobulin alpha Fc receptor; CD89; IgA Fc receptor; Fc alpha receptor; |
Gene ID : | 2204 |
mRNA Refseq : | NM_002000 |
Protein Refseq : | NP_001991 |
MIM : | 147045 |
UniProt ID : | P24071 |
Products Types
◆ Recombinant Protein | ||
FCAR-030H | Recombinant Human FCAR Protein, His-tagged | +Inquiry |
FCAR-666H | Recombinant Human FCAR protein(Met1-Asn227), His-tagged | +Inquiry |
FCAR-3983H | Recombinant Human FCAR Protein, GST-tagged | +Inquiry |
FCAR-2047H | Recombinant Human FCAR Protein, Fc/His-tagged | +Inquiry |
FCAR-3982H | Recombinant Human FCAR Protein, His-tagged | +Inquiry |
◆ Lysates | ||
FCAR-3040HCL | Recombinant Human FCAR cell lysate | +Inquiry |
FCAR-1929RCL | Recombinant Rat FCAR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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