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Recombinant Human FCAR Protein, His-tagged

Cat.No. : FCAR-213H
Product Overview : Recombinant Human FCAR(22-227aa) fused with His tag at C-terminal was expressed in Insect cells.
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  • Gene Information
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Description : FCAR, also known as immunoglobulin alpha Fc receptor isoform, is a member of the multichain immune recognition receptor family which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. It plays a role in both pro- and anti-inflammatory responses depending on the state of IgA bound. It is also an important Fc receptor for neutrophil killing of tumor cells. When FCAR expressing neutrophils come into contact with IgA-opsonized tumor cells, the neutrophils not only perform antibody-dependent cell-mediated cytotoxicity, but also release the cytokines TNF-alpha and IL-1beta which cause increased neutrophil migration to the site.
Source : Insect cells
Species : Human
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass : 24.5kDa (215aa) 28-40kDa (SDS-PAGE under reducing conditions)
Protein length : 22-227aa
AA Sequence : ADPQEGDFPM PFISAKSSPV IPLDGSVKIQ CQAIREAYLT QLMIIKNSTY REIGRRLKFW NETDPEFVID HMDANKAGRY QCQYRIGHYR
FRYSDTLELV VTGLYGKPFL SADRGLVLMP GENISLTCSS AHIPFDRFSL AKEGELSLPQ HQSGEHPANF SLGPVDLNVS GIYRCYGWYN
RSPYLWSFPS NALELVVTDS IHQDYTTQNH HHHHH
Purity : > 85% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.25mg/ml (determined by Absorbance at 280nm)
Gene Name : FCAR Fc fragment of IgA, receptor for [ Homo sapiens ]
Official Symbol : FCAR
Synonyms : FCAR; Fc fragment of IgA, receptor for; immunoglobulin alpha Fc receptor; CD89; IgA Fc receptor; Fc alpha receptor;
Gene ID : 2204
mRNA Refseq : NM_002000
Protein Refseq : NP_001991
MIM : 147045
UniProt ID : P24071

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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