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Recombinant Human FCAR protein, His & GST-tagged

Cat.No. : FCAR-6909H
Product Overview : Recombinant Human FCAR aa. (Gln22~Asn227 (Accession # P24071)) fused with N-terminal His & GST tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Description : This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Source : E. coli
Species : Human
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 55.9kDa
Protein length : Gln22~Asn227 (Accession # P24071)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.3.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : FCAR Fc fragment of IgA receptor [ Homo sapiens (human) ]
Official Symbol : FCAR
Synonyms : FCAR; Fc fragment of IgA receptor; CD89; FcalphaRI; CTB-61M7.2; immunoglobulin alpha Fc receptor; FCAR variant 14; Fc alpha receptor; Fc fragment of IgA, receptor for
Gene ID : 2204
mRNA Refseq : NM_002000.3
Protein Refseq : NP_001991.1
UniProt ID : P24071

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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