Recombinant Human FCAR Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | FCAR-2297H |
| Product Overview : | FCAR MS Standard C13 and N15-labeled recombinant protein (NP_001991) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 32.3 kDa |
| AA Sequence : | MDPKQTTLLC LVLCLGQRIQ AQEGDFPMPF ISAKSSPVIP LDGSVKIQCQ AIREAYLTQL MIIKNSTYRE IGRRLKFWNE TDPEFVIDHM DANKAGRYQC QYRIGHYRFR YSDTLELVVT GLYGKPFLSA DRGLVLMPGE NISLTCSSAH IPFDRFSLAK EGELSLPQHQ SGEHPANFSL GPVDLNVSGI YRCYGWYNRS PYLWSFPSNA LELVVTDSIH QDYTTQNLIR MAVAGLVLVA LLAILVENWH SHTALNKEAS ADVAEPSWSQ QMCQPGLTFA RTPSVCKTRT RPLEQKLISE EDLAANDILD YKDDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | FCAR Fc fragment of IgA receptor [ Homo sapiens (human) ] |
| Official Symbol : | FCAR |
| Synonyms : | FCAR; Fc fragment of IgA, receptor for; immunoglobulin alpha Fc receptor; CD89; IgA Fc receptor; Fc alpha receptor; |
| Gene ID : | 2204 |
| mRNA Refseq : | NM_002000 |
| Protein Refseq : | NP_001991 |
| MIM : | 147045 |
| UniProt ID : | P24071 |
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◆ Lysates
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