Recombinant Human FCGR3B protein, His & T7-tagged

• Cat.No.: FCGR3B-6752H
• Product Overview: Recombinant Human FCGR3B aa. (Pro24~Ser203 (Accession # O75015)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 24.2kDa.
• Protein length: Pro24~Ser203 (Accession # O75015)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.9.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: FCGR3B Fc fragment of IgG receptor IIIb [ Homo sapiens (human) ]
• Official Symbol: FCGR3B
• Synonyms: CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor IIIb; Fc-gamma receptor IIIb (CD 16); fc-gamma RIII-beta; fc-gamma RIIIb; igG Fc receptor III-1; low affinity immunoglobulin gamma Fc region receptor III-B
• Gene ID: 2215
• mRNA Refseq: NM_000570.4
• Protein Refseq: NP_000561.3
• UniProt ID: O75015