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Recombinant Human FES Protein, GST-tagged

Cat.No. : FES-4078H
Product Overview : Human FES full-length ORF ( AAH35357, 1 a.a. - 822 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 116.16 kDa
AA Sequence : MGFSSELCSPQGHGVLQQMQEAELR LLEGMRKWMAQRVKSDREYAGLLHH MSLQDSGGQSRAISPDSPISQSWAE ITSQTEGLSRLLRQHAEDLNSGPLS KLSLLIRERQQLRKTYSEQWQQLQQ ELTKTHSQDIEKLKSQYRALARDSA QAKRKYQEASKDKDRDKAKDKYVRS LWKLFAHHNRYVLGVRAAQLHHQHH HQLLLPGLLRSLQDLHEEMACILKE ILQEYLEISSLVQDEVVAIHREMAA AAARIQPEAEYQGFLRQYGSAPDVP PCVTFDESLLEEGEPLEPGELQLNE LTVESVQHTLTSVTDELAVATEMVF RRQEMVTQLQQELRNEEENTHPRER VQLLGKRQVLQEALQGLQVALCSQA KLQAQQELLQTKLEHLGPGEPPPVL LLQDDRHSTSSSEQEREGGRTPTLE ILKSHISGIFRPKFSLPPPLQLIPE VQKPLHEQLWYHGAIPRAEVAELLV HSGDFLVRESQGKQEYVLSVLWDGL PRHFIIQSLDNLYRLEGEGFPSIPL LIDHLLSTQQPLTKKSGVVLHRAVP KDKWVLNHEDLVLGEQIGRGNFGEV FSGRLRADNTLVAVKSCRETLPPDL KAKFLQEARILKQYSHPNIVRLIGV CTQKQPIYIVMELVQGGDFLTFLRT EGARLRVKTLLQMVGDAAAGMEYLE SKCCIHRDLAARNCLVTEKNVLKIS DFGMSREEADGVYAASGGLRQVPVK WTAPEALNYGRYSSESDVWSFGILL WETFSLGASPYPNLSNQQTREFVEK GGRLPCPELCPDAVFRLMEQCWAYE PGQRPSFSTIYQELQSIRKRHR
Applications : Kinase Assay
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : FES feline sarcoma oncogene [ Homo sapiens ]
Official Symbol : FES
Synonyms : FES; feline sarcoma oncogene; feline sarcoma (Snyder Theilen) viral (v fes)/Fujinami avian sarcoma (PRCII) viral (v fps) oncogene homolog; tyrosine-protein kinase Fes/Fps; c fes/fps protein; FPS; Oncogene FES; feline sarcoma virus; p93c-fes; proto-oncogene c-Fes; proto-oncogene c-Fps; Oncogene FES, feline sarcoma virus; proto-oncogene tyrosine-protein kinase Fes/Fps; feline sarcoma/Fujinami avian sarcoma oncogene homolog; feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog;
Gene ID : 2242
mRNA Refseq : NM_001143783
Protein Refseq : NP_001137255
MIM : 190030
UniProt ID : P07332

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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