Recombinant Human FGB Protein, GST-tagged

• Cat.No.: FGB-4088H
• Product Overview: Human FGB partial ORF ( NP_005132, 392 a.a. - 491 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 36.74 kDa
• AA Sequence: GENRTMTIHNGMFFSTYDRDNDGWL TSDPRKQCSKEDGGGWWYNRCHAAN PNGRYYWGGQYTWDMAKHGTDDGVV WMNWKGSWYSMRKMSMKIRPFFPQQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FGB fibrinogen beta chain [ Homo sapiens ]
• Official Symbol: FGB
• Synonyms: FGB; fibrinogen beta chain; fibrinogen, B beta polypeptide; MGC104327; MGC120405
• Gene ID: 2244
• mRNA Refseq: NM_001184741
• Protein Refseq: NP_001171670
• MIM: 134830
• UniProt ID: P02675