Recombinant Human FGB Protein, GST-tagged

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Recombinant Human FGB Protein, GST-tagged

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Cat.No. : FGB-4088H
Product Overview : Human FGB partial ORF ( NP_005132, 392 a.a. - 491 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.74 kDa
AA Sequence : GENRTMTIHN GMFFSTYDRD NDGWLTSDPR KQCSKEDGGG WWYNRCHAAN PNGRYYWGGQ YTWDMAKHGT DDGVVWMNWK GSWYSMRKMS MKIRPFFPQQ
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : FGB fibrinogen beta chain [ Homo sapiens ]
Official Symbol : FGB
Synonyms : FGB; fibrinogen beta chain; fibrinogen, B beta polypeptide; MGC104327; MGC120405;
Gene ID : 2244
mRNA Refseq : NM_001184741
Protein Refseq : NP_001171670
MIM : 134830
UniProt ID : P02675
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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