"FGF18" Related Products

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Recombinant Human FGF18 Protein, His-tagged

Cat.No.: FGF18-504H
Product Overview: Recombinant human FGF18 (O76093) (Met 1-Ala 207) was fused with a polyhistidine tag at the C-terminus.
Source: HEK293
Species: Human
Tag: His
Predicted N Terminal: Glu 28
Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
Bio-activity: 1. Measured by its binding ability in a functional ELISA.2. Immobilized human FGF18 (Cat: 13206-H08H) at 10 μg/mL (100 μl/well) can bind Rat FGFR4 (Cat:80093-R02H), The EC50 of Rat FGFR4 (Cat:80093-R02H) is 1.17 μg/mL.
Molecular Mass: The secreted recombinant human FGF18 comprises 191 amino acids and has a predicted molecular mass of 22.3 kDa. The apparent molecular mass of rh FGF18 is approximately 32 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: >92 % as determined by SDS-PAGE.
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: FGF18 fibroblast growth factor 18 [ Homo sapiens ]
Official Symbol: FGF18
Synonyms: FGF18; fibroblast growth factor 18; FGF 18; ZFGF5; FGF-18;
Gene ID: 8817
mRNA Refseq: NM_003862
Protein Refseq: NP_003853
MIM: 603726
UniProt ID: O76093
Chromosome Location: 5q34
Pathway: Downstream signaling of activated FGFR, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR2 ligand binding and activation, organism-specific biosystem; FGFR2c ligand binding and activation, organism-specific biosystem; FGFR3 ligand binding and activation, organism-specific biosystem; FGFR3b ligand binding and activation, organism-specific biosystem;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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