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Active Recombinant Human FGF20 Protein

Cat.No. : FGF20-033H
Product Overview : The mature recombinant human FGF-20 protein consists of 211 amino acids (1-211) without tag was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.
Source : E. coli
Species : Human
Bio-activity : Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 0.2-1 ng/mL in the presence of 1 μg/mL of heparin.
Molecular Mass : 24 kDa
Product-Related Proteins : 1-211
Endotoxin : < 0.1 EU/μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : At -80 centigrade. Avoid repeated freeze-thaw cycles.
Storage Buffer : PBS
Gene Name : FGF20 fibroblast growth factor 20 [ Homo sapiens (human) ]
Official Symbol : FGF20
Synonyms : FGF20; fibroblast growth factor 20; RHDA2; FGF-20; fibroblast growth factor 20
Gene ID : 26281
mRNA Refseq : NM_019851
Protein Refseq : NP_062825
MIM : 605558
UniProt ID : Q9NP95

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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