FGF4-038H
Optional Service: Optional requirements on this protein
Product Overview :
The mature recombinant human FGF-4 protein consists of 153 amino acids (54-206) without tag was expressed in E. coli.
Description :
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
Source :
E. coli
Species :
Human
Bio-activity :
Measured in a cell proliferation assay using NR6R3T3 mouse fibroblast cells. The ED50 for this effect is 0.25-1.25 ng/mL.
Molecular Mass :
19.7 kDa
Product-Related Proteins :
54-206
Endotoxin :
< 0.1 EU/μg of the protein as determined by the LAL method
Purity :
> 95 % as determined by SDS-PAGE
Storage :
At -80 centigrade. Avoid repeated freeze-thaw cycles.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.