Active Recombinant Human FGF6 Protein

• Cat.No.: FGF6-89H
• Product Overview: Recombinant Human FGF6 Protein without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: Fibroblast growth factor 6 (FGF-6) is a heparin-binding growth factor that is expressed in epithelial and mesenchymal lineages. FGF-6 binds and signals through the FGF receptors FGFR1, FGFR2, and FGFR4. FGF-6 functions as a mitogen for vascular endothelial cells and fibroblasts. FGF-6 is also an important factor driving muscle differentiation and regeneration.
• Bio-activity: 3T3 Proliferation w 1 ug heparin, ≤1 ng/mL; ≥1.0 x 10^6 units/mg
• Molecular Mass: Monomer, 18.9 kDa (169 aa)
• AA Sequence: MGTRANNTLLDSRGWGTLLSRSRAGLAGEIAGVNWESGYLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTHEENPYSLLEISTVERGVVSLFGVRSALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYQGTYIALSKYGRVKRGSKVSPIMTVTHFLPRI
• Endotoxin: ≤1 EUs/μg, Kinetic LAL
• Purity: ≥95%, Reducing and Non-Reducing SDS PAGE
• Stability: 12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
  1 month when stored at 4 centigrade after reconstituting as directed.
  3 months when stored at -20 to -80 centigrade after reconstituting as directed.
• Storage: Storage Prior to Reconstitution: -20 centigrade
• Storage Buffer: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate and 50 mM sodium chloride, pH 7.5
• Reconstitution: Sterile water at 0.1 mg/mL
• Shipping: Room temperature
• Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. If a precipitate is observed, centrifuge the solution thoroughly and use only the soluble fraction (removing it from the precipitate). A 10% overfill has been added to compensate for any loss of protein in the precipitate. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.

Gene Information

• Gene Name: FGF6 fibroblast growth factor 6 [ Homo sapiens (human) ]
• Official Symbol: FGF6
• Synonyms: FGF6; fibroblast growth factor 6; FGF-6; HST-2; HSTF-2; heparin-binding growth factor 6; heparin secretory-transforming protein 2; HST2; HBGF-6
• Gene ID: 2251
• mRNA Refseq: NM_020996
• Protein Refseq: NP_066276
• MIM: 134921
• UniProt ID: P10767