Recombinant Human FGFR1 protein, His-tagged
Cat.No. : | FGFR1-18H |
Product Overview : | Recombinant Human FGFR1 protein (Arg22-Ile376), fused to His tag at C-terminus, was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Fibroblast growth factor receptor 1 (FGFR1) is also known as basic fibroblast growth factor receptor 1(BFGFR1), FMS-like tyrosine kinase, CD331, and is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. This protein is one of several fibroblast growth factor receptors, which are related proteins that are involved in important processes such as cell division, regulation of cell growth and maturation, formation of blood vessels, wound healing, and embryonic development.The FGFR1 protein spans the cell membrane, so that one end of the protein remains inside the cell and the other end projects from the outer surface of the cell. This positioning allows the FGFR1 protein to interact with specific growth factors outside the cell and to receive signals that help the cell respond to its environment. When growth factors attach to the FGFR1 protein, the receptor triggers a cascade of chemical reactions inside the cell that instruct the cell to undergo certain changes, such as maturing to take on specialized functions. The FGFR1 protein is thought to play an important role in the development of the nervous system. This protein may also help regulate the growth of long bones, such as the large bones in the arms and legs. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 42.5 kDa. The protein migrates as 60-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | 355 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | FGFR1 |
Official Symbol : | FGFR1 |
Synonyms : | FGFR1; fibroblast growth factor receptor 1; FLT2, fms related tyrosine kinase 2 , KAL2; BFGFR; CD331; CEK; FLG; H2; H3; H4; H5; N SAM; Pfeiffer syndrome; FGFR1/PLAG1 fusion; proto-oncogene c-Fgr; FMS-like tyrosine kinase 2; hydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1; OGD; FLT2; KAL2; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; bFGF-R-1; FLJ99988 |
Gene ID : | 2260 |
mRNA Refseq : | NM_001174063 |
Protein Refseq : | NP_001167534 |
MIM : | 136350 |
UniProt ID : | P11362 |
Products Types
◆ Recombinant Protein | ||
FGFR1-1275H | Acitve Recombinant Human FGFR1 protein(Met1-Lys310), hFc-tagged | +Inquiry |
Fgfr1-4015M | Active Recombinant Mouse Fgfr1 protein(Met1-Glu376), hFc-tagged | +Inquiry |
FGFR1-4121H | Active Recombinant Human FGFR1 Protein, GST/His-tagged | +Inquiry |
FGFR1-2056H | Recombinant Human FGFR1 Protein, His-tagged | +Inquiry |
FGFR1-5C | Recombinant Cynomolgus Monkey FGFR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FGFR1-2765HCL | Recombinant Human FGFR1 cell lysate | +Inquiry |
FGFR1-2133MCL | Recombinant Mouse FGFR1 cell lysate | +Inquiry |
FGFR1-476HCL | Recombinant Human FGFR1 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1557 | U2OS FGFR1 Bioassay Kit | +Inquiry |
Kit-1590 | FGFR1 Functional Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionDEFB103A plays a role in maintaining a balanced microbiome by exerting selective antimicrobial activity. Understanding this interaction is crucial for potential applications in microbiome-related disorders.
Research suggests that altered levels of DEFB103A expression may be associated with certain diseases. However, its specific use as a diagnostic marker requires further validation.
While research is ongoing, potential side effects and concerns related to the therapeutic use of DEFB103A or its analogs need to be thoroughly investigated, including any possible immunogenicity.
DEFB103A plays a crucial role in the innate immune system by acting as an antimicrobial peptide. It helps defend the body against a wide range of pathogens, including bacteria, viruses, and fungi.
DEFB103A deficiency has been linked to an increased susceptibility to various infections, particularly those affecting the skin and mucosal surfaces.
Customer Reviews (3)
Write a reviewFGFR1, a calcium-dependent phospholipid-binding protein, plays a crucial role in various cellular processes, making it a valuable tool for investigation.
When combined with the support and quality assurance provided by the manufacturer, researchers can confidently utilize FGFR1 protein to unravel the intricate mechanisms underlying cellular processes, ultimately advancing scientific knowledge.
The manufacturer can contribute to the research process by providing top-quality FGFR1 protein that meets rigorous standards of purity, stability, and reliability.
Ask a Question for All FGFR1 Products
Required fields are marked with *
My Review for All FGFR1 Products
Required fields are marked with *
Inquiry Basket