Recombinant Human FGFR3 protein, His-Avi-tagged
Cat.No. : | FGFR3-607H |
Product Overview : | Recombinant Human FGFR3 alpha (IIIc) Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains Glu23-Gly375. |
- Specification
- Gene Information
- Related Products
Description : | Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Molecular Mass : | The protein has a predicted MW of 41.1 KDa. Due to glycosylation, the protein migrates to 65- 75KDa based on Bis-Tris PAGE result. |
Protein length : | Glu23-Gly375 |
Endotoxin : | Less than 0.05EU per ug by the LAL method. |
Purity : | > 95% as determined by Teis-Bis PAGE; > 95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Gene Name : | FGFR3 fibroblast growth factor receptor 3 [Homo sapiens (human)] |
Official Symbol : | FGFR3 |
Synonyms : | CD333; CEK; EC 2.7.10; FGF R3; FGFR3; fibroblast growth factor receptor 3; HSFGFR3EX; JTK4; JTK4thanatophoric dwarfism |
Gene ID : | 2261 |
mRNA Refseq : | NM_000142.5 |
Protein Refseq : | NP_000133.1 |
MIM : | 134934 |
UniProt ID : | P22607 |
Products Types
◆ Recombinant Protein | ||
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Fgfr3-624M | Active Recombinant Mouse Fgfr3 protein(Met1-Tyr367), His-tagged | +Inquiry |
FGFR3-207H | Recombinant Human FGFR3 Protein, hIgG-His-tagged | +Inquiry |
FGFR3-4136H | Active Recombinant Human FGFR3 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
FGFR3-001CCL | Recombinant Cynomolgus FGFR3 cell lysate | +Inquiry |
FGFR3-2596MCL | Recombinant Mouse FGFR3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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