Recombinant Human FGFR4 protein, His-Avi-tagged, Biotinylated

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Recombinant Human FGFR4 protein, His-Avi-tagged, Biotinylated

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Cat.No. : FGFR4-062HB
Product Overview : Biotinylated Recombinant Human FGFR4 Protein is expressed from mammalian with a His tag and Avi Tag at the C-terminal. It contains Leu22-Asp369.
Description : Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19.
Source : HEK293
Species : Human
Tag : His-Avi
Form : Supplied as 0.22um filtered solution in PBS (pH 7.4).
Molecular Mass : The protein has a predicted MW of 41.4 kDa.Due to glycosylation, the protein migrates to 55-72 KDa based on Bis-Tris PAGE result.
Protein length : It contains Leu22-Asp369.
Endotoxin : Less than 0.05 EU per ug by the LAL method.
Purity : > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :

HPLC data :

Gene Name : FGFR4 fibroblast growth factor receptor 4 [ Homo sapiens ]
Official Symbol : FGFR4
Synonyms : CD334 antigen; CD334; EC 2.7.10; EC 2.7.10.1; FGF R4; FGFR4; FGFR-4; fibroblast growth factor receptor 4; JTK2hydroxyaryl-protein kinase; MGC20292; protein-tyrosine kinase; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Gene ID : 2264
mRNA Refseq : NM_002011
Protein Refseq : NP_002002
MIM : 134935
UniProt ID : P22455

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