Recombinant Human Fibroblast Growth Factor 7, His-tagged FGF7-594H

Recombinant Human Fibroblast Growth Factor 7, His-tagged


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Cat.No. : FGF7-594H Optional Service: Optional requirements on this protein
Product Overview : FGF7 contains a polyhistidine tag at C-terminus and has a calculated MW of 18.9 kDa after removal of signal peptide.
Description : Fibroblast Growth Factor 7 (FGF7), also known as Keratinocyte Growth Factor (KGF), is a paracrine-acting, epithelial mitogen produced by cells of mesenchymal origin. It is a member of the fibroblast growth factor (FGF) family, and acts exclusively through a subset of FGF receptor isoforms (FGFR2b) expressed predominantly by epithelial cells. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells.
Source : Recombinant Human Fibroblast Growth Factor 7, Cys33?CThr194 (Accession NP_002000.1) was expressed in HEK293.
Species : Human
Form : Bulk protein in a 0.22 μm filtered solution of PBS, pH7.4 and delivered as liquid formulation or lyophilized powder. Normally 5-8% trehalose and mannitol are added as protectants before lyophilization.
Purity : >97% purity as determined by SDS-PAGE of reduced FGF7.
Endotoxin : Less than 0.01ng endotoxin per μg FGF7.
Storage : Store at -80°C upon received. Avoid repeated freeze-thaw cycles.
PDB rendering based on 1qqk. :

Gene Name : FGF7 fibroblast growth factor 7 [ Homo sapiens ]
Official Symbol : FGF7
Synonyms : FGF7; fibroblast growth factor 7; KGF; HBGF-7; FGF-7; keratinocyte growth factor; heparin-binding growth factor 7; fibroblast growth factor 7 (keratinocyte growth factor); OTTHUMP00000162252
Gene ID : 2252
mRNA Refseq : NM_002009
Protein Refseq : NP_002000
MIM : 148180
UniProt ID : P21781
Chromosome Location : 15q21.2
Pathway : MAPK signaling pathway; Melanoma; Prostate cancer; Regulation of actin cytoskeleton; Signaling by FGFR
Function : growth factor activity; chemoattractant activity; heparin binding; type 2 fibroblast growth factor receptor binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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