Recombinant Human Fibroblast Growth Factor 7, His-tagged
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Cat.No. : | FGF7-594H Optional Service: Optional requirements on this protein |
Product Overview : | FGF7 contains a polyhistidine tag at C-terminus and has a calculated MW of 18.9 kDa after removal of signal peptide. |
Description : | Fibroblast Growth Factor 7 (FGF7), also known as Keratinocyte Growth Factor (KGF), is a paracrine-acting, epithelial mitogen produced by cells of mesenchymal origin. It is a member of the fibroblast growth factor (FGF) family, and acts exclusively through a subset of FGF receptor isoforms (FGFR2b) expressed predominantly by epithelial cells. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. |
Source : | Recombinant Human Fibroblast Growth Factor 7, Cys33?CThr194 (Accession NP_002000.1) was expressed in HEK293. |
Species : | Human |
Form : | Bulk protein in a 0.22 μm filtered solution of PBS, pH7.4 and delivered as liquid formulation or lyophilized powder. Normally 5-8% trehalose and mannitol are added as protectants before lyophilization. |
Purity : | >97% purity as determined by SDS-PAGE of reduced FGF7. |
Endotoxin : | Less than 0.01ng endotoxin per μg FGF7. |
Storage : | Store at -80°C upon received. Avoid repeated freeze-thaw cycles. |
PDB rendering based on 1qqk. : |
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Gene Name : | FGF7 fibroblast growth factor 7 [ Homo sapiens ] |
Official Symbol : | FGF7 |
Synonyms : | FGF7; fibroblast growth factor 7; KGF; HBGF-7; FGF-7; keratinocyte growth factor; heparin-binding growth factor 7; fibroblast growth factor 7 (keratinocyte growth factor); OTTHUMP00000162252 |
Gene ID : | 2252 |
mRNA Refseq : | NM_002009 |
Protein Refseq : | NP_002000 |
MIM : | 148180 |
UniProt ID : | P21781 |
Chromosome Location : | 15q21.2 |
Pathway : | MAPK signaling pathway; Melanoma; Prostate cancer; Regulation of actin cytoskeleton; Signaling by FGFR |
Function : | growth factor activity; chemoattractant activity; heparin binding; type 2 fibroblast growth factor receptor binding |
◆ Recombinant Protein
FGF7-1498H | Recombinant Human FGF7 Protein, His&GST-tagged | +Inquiry |
Fgf7-1499R | Recombinant Rat Fgf7 Protein, His&GST-tagged | +Inquiry |
FGF7-5416H | Recombinant Human Fibroblast Growth Factor 7 | +Inquiry |
FGF7-90H | Recombinant Human FGF7 Protein | +Inquiry |
Fgf7-2999M | Recombinant Mouse Fgf7 Protein, Myc/DDK-tagged | +Inquiry |
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◆ Lysates
FGF7-6236HCL | Recombinant Human FGF7 293 Cell Lysate | +Inquiry |
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FGF1FGF10FGF12FGF16FGF17FGF18FGF19FGF2FGF20Fgf21Fgf22FGF23FGF4FGF5FGF6FGF7FGF8FGF9Fgf15FGF11FGF3FGF13FGF14
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