Recombinant Human Filaggrin

• Cat.No.: FLG-1220H
• Product Overview: Recombinant human FLGis Expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: FLG are animportant class of the intermediate filament-associated proteins whichinterectwith keratin intermediate filaments (Ifs) of terminally differentiating mammalianepidermis. FLG exhibitwide species variations. FLG also appears to bea target molecula for rheumatoid arthritis-specific auto-antibodies inhumans.
• Form: Recombinant Human FLGprotein (a.a.3838-4062) at 100 μg/ml in 50 mM Tris-Acetate + pH 7.5 + 1 mMEDTA + 20% Glycerol.
• Storage: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stablefor 12 months. Please avoid freeze-thaw cycles.
• OfficialSymbol: FLG

Gene Information

• Gene Name: FLG filaggrin [ Homo sapiens]
• Synonyms: FLG; filaggrin; ATOD2;epidermal filaggrin; OTTHUMP00000014057
• Gene ID: 2312
• mRNA Refseq: NM_002016
• Protein Refseq: NP_002007
• MIM: 135940
• UniProt ID: P20930
• Chromosome Location: 1q21.3
• Function: calcium ion binding; structuralmolecule activity; nucleoside-triphosphatase activity