Recombinant Human FIP1L1 Protein (S2-E594), His/GST tagged

• Cat.No.: FIP1L1-0308H
• Product Overview: Recombinant Human 8His-GST-TEV-GG-FIP1L1(S2-E594 end) Protein was expressed in Insect cell.

Specification

• Description: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex.
• Source: Insect cell
• Species: Human
• Tag: His/GST
• Form: Liquid
• Protein Length: S2-E594
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: FIP1L1 FIP1 like 1 (S. cerevisiae) [ Homo sapiens (human) ]
• Official Symbol: FIP1L1
• Synonyms: FIP1L1; FIP1 like 1 (S. cerevisiae); pre-mRNA 3-end-processing factor FIP1; DKFZp586K0717; FIP1-like 1 protein; factor interacting with PAP; rearranged in hypereosinophilia; Rhe; hFip1; FLJ33619
• Gene ID: 81608
• mRNA Refseq: NM_001134937
• Protein Refseq: NP_001128409
• MIM: 607686
• UniProt ID: Q6UN15