| Description : |
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
83 kDa |
| Protein Length : |
1338 |
| AA Sequence : |
MVSYWDTGVLLCALLSCLLLTGSSS GSKLKDPELSLKGTQHIMQAGQTLH LQCRGEAAHKWSLPEMVSKESERLS ITKSACGRNGKQFCSTLTLNTAQAN HTGFYSCKYLAVPTSKKKETESAIY IFISDTGRPFVEMYSEIPEIIHMTE GRELVIPCRVTSPNITVTLKKFPLD TLIPDGKRIIWDSRKGFIISNATYK EIGLLTCEATVNGHLYKTNYLTHRQ TNTIIDVQISTPRPVKLLRGHTLVL NCTATTPLNTRVQMTWSYPDEKNKR ASVRRRIDQSNSHANIFYSVLTIDK MQNKDKGLYTCRVRSGPSFKSVNTS VHIYDKAFITVKHRKQQVLETVAGK RSYRLSMKVKAFPSPEVVWLKDGLP ATEKSARYLTRGYSLIIKDVTEEDA GNYTILLSIKQSNVFKNLTATLIVN VKPQIYEKAVSSFPDPALYPLGSRQ ILTCTAYGIPQPTIKWFWHPCNHNH SEARCDFCSNNEESFILDADSNMGN RIESITQRMAIIEGKNKMASTLVVA DSRISGIYICIASNKVGTVGRNISF YITDVPNGFHVNLEKMPTEGEDLKL SCTVNKFLYRDVTWILLRTVNNRTM HYSISKQKMAITKEHSITLNLTIMN VSLQDSGTYACRARNVYTGEEILQK KEITIRDQEAPYLLRNLSDHTVAIS SSTTLDCHANGVPEPQITWFKNNHK IQQEPGIILGPGSSTLFIERVTEED EGVYHCKATNQKGSVESSAYLTVQG TSDKSNLELITLTCTCVAATLFWLL LTLFIRKMKRSSSEIKTDYLSIIMD PDEVPLDEQCERLPYDASKWEFARE RLKLGKSLGRGAFGKVVQASAFGIK KSPTCRTVAVKMLKEGATASEYKAL MTELKILTHIGHHLNVVNLLGACTK QGGPLMVIVEYCKYGNLSNYLKSKR DLFFLNKDAALHMEPKKEKMEPGLE QGKKPRLDSVTSSESFASSGFQEDK SLSDVEEEEDSDGFYKEPITMEDLI SYSFQVARGMEFLSSRKCIHRDLAA RNILLSENNVVKICDFGLARDIYKN PDYVRKGDTRLPLKWMAPESIFDKI YSTKSDVWSYGVLLWEIFSLGGSPY PGVQMDEDFCSRLREGMRMRAPEYS TPEIYQIMLDCWHRDPKERPRFAEL VEKLGDLLQANVQQDGKDYIPINAI LTGNSGFTYSTPAFSEDFFKESISA PKFNSGSSDDVRYVNAFKFMSLERI KTFEELLPNATSMFDDYQGDSSTLL ASPMLKRFTWTDSKPKASLKIDLRV TSKSKESGLSDVSRPSFCHSSCGHV SEGKRRFTYDHAELERKIACCSPPP DYNSVVLYSTPPI |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
