"FLT1" Related Products

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Recombinant Human FLT1 Protein, MYC/DDK-tagged

Cat.No.: FLT1-2341H
Product Overview: Recombinant human FLT1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
Description: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
Source: HEK293
Species: Human
Tag : MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 148 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) [ Homo sapiens ]
Official Symbol: FLT1
Synonyms: FLT; FLT-1; VEGFR-1; VEGFR1
Gene ID: 2321
mRNA Refseq: NM_001159920
Protein Refseq: NP_001153392
MIM: 165070
UniProt ID: P17948

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