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Recombinant Human FLT3 Protein, MYC/DDK-tagged
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Cat.No. : | FLT3-2340H |
Product Overview : | Recombinant human FLT3 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293 |
Description : | This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015] |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 112.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | FLT3 fms-related tyrosine kinase 3 [ Homo sapiens ] |
Official Symbol : | FLT3 |
Synonyms : | CD135; FLK-2; FLK2; STK1 |
Gene ID : | 2322 |
mRNA Refseq : | NM_004119 |
Protein Refseq : | NP_004110 |
MIM : | 136351 |
UniProt ID : | P36888 |
◆ Recombinant Protein
FLT3-4371H | Recombinant Human FLT3 Protein, GST-tagged | +Inquiry |
FLT3-1155R | Recombinant Rhesus Monkey FLT3 Protein, His-tagged | +Inquiry |
FLT3-4370H | Recombinant Human FLT3 Protein, GST-tagged | +Inquiry |
FLT3-088H | Recombinant Human FLT3 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
FLT3-140H | Recombinant Human Fms-related Tyrosine Kinase 3, Fc Chimera | +Inquiry |
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◆ Lysates
FLT3-2561HCL | Recombinant Human FLT3 cell lysate | +Inquiry |
FLT3-970MCL | Recombinant Mouse FLT3 cell lysate | +Inquiry |
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◆ Assay kits
Kit-1593 | Flt3 Activity Assay Kit | +Inquiry |
Kit-1592 | Flt3 ActivityAssay Kit | +Inquiry |
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