|Product Overview:||Human PDK4 (NP_002603.1, 1 a.a. - 411 a.a.) full-length recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells.|
|Description:||This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq|
|Bio-activity:||The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
ATP: 100 μM.
|Molecular Mass:||83 kDa|
|Purity:||59 % by SDS-PAGE/CBB staining|
|Storage:||Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.|
|Storage Buffer:||In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol)|
|Gene Name:||FLT4 fms-related tyrosine kinase 4 [ Homo sapiens ]|
|Synonyms:||FLT4; fms-related tyrosine kinase 4; vascular endothelial growth factor receptor 3; PCL; VEGFR3; FLT-4; VEGFR-3; soluble VEGFR3 variant 1; soluble VEGFR3 variant 2; soluble VEGFR3 variant 3; fms-like tyrosine kinase 4; tyrosine-protein kinase receptor FLT4; FLT41; LMPH1A;|