Recombinant Human FMR1 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | FMR1-4354H |
| Product Overview : | FMR1 MS Standard C13 and N15-labeled recombinant protein (NP_002015) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 71 kDa |
| AA Sequence : | MEELVVEVRG SNGAFYKAFV KDVHEDSITV AFENNWQPDR QIPFHDVRFP PPVGYNKDIN ESDEVEVYSR ANEKEPCCWW LAKVRMIKGE FYVIEYAACD ATYNEIVTIE RLRSVNPNKP ATKDTFHKIK LDVPEDLRQM CAKEAAHKDF KKAVGAFSVT YDPENYQLVI LSINEVTSKR AHMLIDMHFR SLRTKLSLIM RNEEASKQLE SSRQLASRFH EQFIVREDLM GLAIGTHGAN IQQARKVPGV TAIDLDEDTC TFHIYGEDQD AVKKARSFLE FAEDVIQVPR NLVGKVIGKN GKLIQEIVDK SGVVRVRIEA ENEKNVPQEE EIMPPNSLPS NNSRVGPNAP EEKKHLDIKE NSTHFSQPNS TKVQRVLVAS SVVAGESQKP ELKAWQGMVP FVFVGTKDSI ANATVLLDYH LNYLKEVDQL RLERLQIDEQ LRQIGASSRP PPNRTDKEKS YVTDDGQGMG RGSRPYRNRG HGRRGPGYTS GTNSEASNAS ETESDHRDEL SDWSLAPTEE ERESFLRRGD GRRRGGGGRG QGGRGRGGGF KGNDDHSRTD NRPRNPREAK GRTTDGSLQI RVDCNNERSV HTKTLQNTSS EGSRLRTGKD RNQKKEKPDS VDGQQPLVNG VPTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | FMR1 fragile X mental retardation 1 [ Homo sapiens (human) ] |
| Official Symbol : | FMR1 |
| Synonyms : | FMR1; fragile X mental retardation 1; POF, POF1, premature ovarian failure 1; fragile X mental retardation protein 1; FMRP; FRAXA; MGC87458; protein FMR-1; fragile X mental retardation 1 protein; POF; POF1; |
| Gene ID : | 2332 |
| mRNA Refseq : | NM_002024 |
| Protein Refseq : | NP_002015 |
| MIM : | 309550 |
| UniProt ID : | Q06787 |
◆ Recombinant Protein
| Fmr1-3058M | Recombinant Mouse Fmr1 Protein, Myc/DDK-tagged | +Inquiry |
| FMR1-4396H | Recombinant Human FMR1 Protein, GST-tagged | +Inquiry |
| FMR1-12948H | Recombinant Human FMR1, GST-tagged | +Inquiry |
| FMR1-446H | Recombinant Human FMR1 protein, MYC/DDK-tagged | +Inquiry |
| FMR1-2372R | Recombinant Rat FMR1 Protein | +Inquiry |
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◆ Lysates
| FMR1-6179HCL | Recombinant Human FMR1 293 Cell Lysate | +Inquiry |
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