Recombinant Human FN3K Protein (Met1-Lys309), His tagged

• Cat.No.: FN3K-3612H
• Product Overview: Recombinant human FN3K (Met1-Lys309) protein fused with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Met1-Lys309
• Description: Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate. Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions. Involved in intracellular deglycation in erythrocytes. Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function. Also able to phosphorylate psicosamines and ribulosamines
• Molecular Mass: 36.16 kDa
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: FN3K fructosamine 3 kinase [ Homo sapiens (human) ]
• Official Symbol: FN3K
• Synonyms: FN3K; fructosamine 3 kinase; fructosamine-3-kinase
• Gene ID: 64122
• mRNA Refseq: NM_022158
• Protein Refseq: NP_071441
• MIM: 608425
• UniProt ID: Q9H479