Recombinant Mouse Fn3k Protein, Myc/DDK-tagged

• Cat.No.: Fn3k-3059M
• Product Overview: Purified recombinant protein of mouse full-length fructosamine 3 kinase (Fn3k), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate. Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions. Involved in intracellular deglycation in erythrocytes and pancreatic islets. Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function. Also able to phosphorylate psicosamines and ribulosamines..
• Molecular Mass: 35 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fn3k fructosamine 3 kinase [ Mus musculus (house mouse) ]
• Official Symbol: Fn3k
• Synonyms: FN3K; fructosamine 3 kinase; fructosamine-3-kinase; 2310074G21Rik
• Gene ID: 63828
• mRNA Refseq: NM_022014
• Protein Refseq: NP_071297
• UniProt ID: Q9ER35