Recombinant Human FNTA Protein, His-tagged

• Cat.No.: FNTA-503H
• Product Overview: Recombinant Human FNTA(Met51~Lys366) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 43.7kDa
• Protein length: Met51~Lys366
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 98%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: FNTA farnesyltransferase, CAAX box, alpha [ Homo sapiens ]
• Official Symbol: FNTA
• Synonyms: FNTA; farnesyltransferase, CAAX box, alpha; protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; FPTA; PGGT1A; protein prenyltransferase alpha subunit repeat containing 2; PTAR2; FTase-alpha; GGTase-I-alpha; farnesyl-protein transferase alpha-subunit; ras proteins prenyltransferase subunit alpha; type I protein geranyl-geranyltransferase alpha subunit; MGC99680
• Gene ID: 2339
• mRNA Refseq: NM_002027
• Protein Refseq: NP_002018
• MIM: 134635
• UniProt ID: P49354