Recombinant Human FOLR2 Protein (19-230 aa), His-tagged

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Recombinant Human FOLR2 Protein (19-230 aa), His-tagged

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Cat.No. : FOLR2-2815H
Product Overview : Recombinant Human FOLR2 Protein (19-230 aa) is produced by Baculovirus expression system. This protein is fused with a 10xHis tag at the N-terminal. Research Area: Metabolism. Protein Description: Partial.
Description : Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
Source : Baculovirus
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 27.1 kDa
Protein length : 19-230 aa
AA Sequence : CSAQDRTDLL NVCMDAKHHK TKPGPEDKLH DQCSPWKKNA CCTASTSQEL HKDTSRLYNF NWDHCGKMEP ACKRHFIQDT CLYECSPNLG PWIQQVNQSW RKERFLDVPL CKEDCQRWWE DCHTSHTCKS NWHRGWDWTS GVNKCPAGAL CRTFESYFPT PAALCEGLWS HSYKVSNYSR GSGRCIQMWF DSAQGNPNEE VARFYAAAMH VN
Purity : > 85% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : FOLR2 folate receptor 2 (fetal) [ Homo sapiens ]
Official Symbol : FOLR2
Synonyms : FOLR2; folate receptor 2 (fetal); folate receptor beta; FBP; folate receptor, beta; FR-P3; FR-BETA; BETA-HFR; FBP/PL-1;
Gene ID : 2350
mRNA Refseq : NM_000803
Protein Refseq : NP_000794
MIM : 136425
UniProt ID : P14207

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