Recombinant Human FOXE1 Protein, GST-tagged

• Cat.No.: FOXE1-4447H
• Product Overview: Human FOXE1 full-length ORF ( AAI52745.1, 1 a.a. - 373 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 67.43 kDa
• AA Sequence: MTAESGPPPPQPEVLATVKEERGET AAGAGVPGEATGRGAGGRRRKRPLQ RGKPPYSYIALIAMAIAHAPERRLT LGGIYKFITERFPFYRDNPKKWQNS IRHNLTLNDCFLKIPREAGRPGKGN YWALDPNAEDMFESGSFLRRRKRFK RSDLSTYPAYMHDAAAAAAAAAAAA AAAAIFPGAVPAARPPYPGAVYAGY APPSLAAPPPVYYPAASPGPCRVFG LVPERPLSPELGPAPSGPGGSCAFA SAGAPATTTGYQPAGCTGARPANPS AYAAAYAGPDGAYPQGAGSAIFAAA GRLAGPASPPAGGSSGGVETTVDFY GRTSPGQFGALGACYNPGGQLGGAS AGAYHARHAAAYPGGIDRFVSAM
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FOXE1 forkhead box E1 (thyroid transcription factor 2) [ Homo sapiens ]
• Official Symbol: FOXE1
• Synonyms: FOXE1; forkhead box E1 (thyroid transcription factor 2); FKHL15, forkhead box E2, FOXE2, TITF2; forkhead box protein E1; HFKH4; TTF 2; forkhead box E2; forkhead box protein E2; HNF-3/fork head-like protein 5; thyroid transcription factor 2; forkhead-related protein FKHL15; forkhead, drosophila, homolog-like 15; TTF2; FOXE2; HFKL5; TITF2; TTF-2; FKHL15
• Gene ID: 2304
• mRNA Refseq: NM_004473
• Protein Refseq: NP_004464
• MIM: 602617
• UniProt ID: O00358