Recombinant Mouse Foxe1 Protein, His-tagged

• Cat.No.: Foxe1-1516M
• Product Overview: Recombinant Mouse Foxe1 Protein (Asn127-Met371) with N-His tag was expressed in E. coli.

Specification

• Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cranial skeletal system development. Acts upstream of or within several processes, including animal organ development; roof of mouth development; and thyroid hormone generation. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; brain; branchial pouch endoderm; head surface ectoderm; and outflow tract. Used to study Bamforth-Lazarus syndrome and congenital hypothyroidism. Human ortholog(s) of this gene implicated in Bamforth-Lazarus syndrome and thyroid gland papillary carcinoma. Orthologous to human FOXE1 (forkhead box E1).
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 27.7 kDa
  Accurate Molecular Mass: 25 kDa
• Protein length: Asn127-Met371
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Foxe1 forkhead box E1 [ Mus musculus (house mouse) ]
• Official Symbol: Foxe1
• Synonyms: FOXE1; forkhead box E1; forkhead box protein E1; TTF-2; thyroid transcription factor 2; Titf2
• Gene ID: 110805
• mRNA Refseq: NM_183298
• Protein Refseq: NP_899121
• UniProt ID: Q8R2I0