Recombinant Human FRS2 Protein, GST-tagged

• Cat.No.: FRS2-4506H
• Product Overview: Human FRS2 full-length ORF ( AAH21562.1, 1 a.a. - 512 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: FRS2 (Fibroblast Growth Factor Receptor Substrate 2) is a Protein Coding gene. Diseases associated with FRS2 include Nasal Cavity Squamous Cell Carcinoma. Among its related pathways are RET signaling and FGF signaling pathway. GO annotations related to this gene include insulin receptor binding and transmembrane receptor protein tyrosine kinase adaptor activity. An important paralog of this gene is FRS3.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 82.72 kDa
• AA Sequence: MGSCCSCPDKDTVPDNHRNKFKVIN VDDDGNELGSGIMELTDTELILYTR KRDSVKWHYLCLRRYGYDSNLFSFE SGRRCQTGQGIFAFKCARAEELFNM LQEIMQNNSINVVEEPVVERNNHQT ELEVPRTPRTPTTPGFAAQNLPNGY PRYPSFGDASSHPSSRHPSVGSARL PSVGEESTHPLLVAEEQVHTYVNTT GVQEERKNRTSVHVPLEARVSNAES STPKEEPSSIEDRDPQILLEPEGVK FVLGPTPVQKQLMEKEKLEQLGRDQ VSGSGANNTEWDTGYDSDERRDAPS VNKLVYENINGLSIPSASGVRRGRL TSTSTSDTQNINNSAQRRTALLNYE NLPSLPPVWEARKLSRDEDDNLGPK TPSLNGYHNNLDPMHNYVNTENVTV PASAHKIEYSRRRDCTPTVFNFDIR RPSLEHRQLNYIQVDLEGGSDSDNP QTPKTPTTPLPQTPTRRTELYAVID IERTAAMSNLQKALPRDDGTSRKTR HNSTDLPMLAWK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FRS2 fibroblast growth factor receptor substrate 2 [ Homo sapiens ]
• Official Symbol: FRS2
• Synonyms: FRS2; fibroblast growth factor receptor substrate 2; FRS2A; FRS2alpha; SNT 1; SNT1; FGFR substrate 2; FGFR signalling adaptor; FGFR-signaling adaptor SNT; suc1-associated neurotrophic factor target 1; SNT; SNT-1
• Gene ID: 10818
• mRNA Refseq: NM_001042555
• Protein Refseq: NP_001036020
• MIM: 607743
• UniProt ID: Q8WU20