Recombinant Human FRS2 protein, MYC/DDK-tagged
Cat.No. : | FRS2-23H |
Product Overview : | Recombinant Human FRS2, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
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Description : | FRS2 played an important role in many functions. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 56.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | FRS2 fibroblast growth factor receptor substrate 2 [ Homo sapiens ] |
Official Symbol : | FRS2 |
Synonyms : | FRS2; fibroblast growth factor receptor substrate 2; FRS2A; FRS2alpha; SNT 1; SNT1; FGFR substrate 2; FGFR signalling adaptor; FGFR-signaling adaptor SNT; suc1-associated neurotrophic factor target 1; SNT; SNT-1; |
Gene ID : | 10818 |
mRNA Refseq : | NM_006654 |
Protein Refseq : | NP_006645 |
MIM : | 607743 |
UniProt ID : | Q8WU20 |
Chromosome Location : | 12q15 |
Pathway : | Downstream signaling of activated FGFR, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; FRS2-mediated cascade, organism-specific biosystem; Frs2-mediated activation, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem; IRS-related events, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem; |
Function : | fibroblast growth factor receptor binding; insulin receptor binding; neurotrophin TRKA receptor binding; phosphatase activator activity; protein binding; transmembrane receptor protein tyrosine kinase adaptor activity; |
Products Types
◆ Recombinant Protein | ||
Frs2-191M | Recombinant Mouse Frs2 Protein, His-tagged | +Inquiry |
Frs2-3087M | Recombinant Mouse Frs2 Protein, Myc/DDK-tagged | +Inquiry |
Frs2-192R | Recombinant Rat Frs2 Protein, His-tagged | +Inquiry |
FRS2-4506H | Recombinant Human FRS2 Protein, GST-tagged | +Inquiry |
FRS2-3367M | Recombinant Mouse FRS2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FRS2-6134HCL | Recombinant Human FRS2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionFRS2 protein regulates signal transduction of insulin receptors, so its abnormal expression or function can lead to the pathogenesis of insulin resistance.
FRS2 plays an important role in the proliferation and differentiation of hepatocytes, and no good regulation will lead to hepatocyte transformation and carcinogenesis.
FRS2 protein can be considered a potential target for the treatment of certain types of cancer, so drug research is expected to further explore this effect.
The bone metabolism regulated by FRS2 protein is related to bone formation and bone resorption, and plays a role by affecting the signaling and function of bone cells.
The protein can affect insulin metabolism by binding to insulin receptors and other proteins to regulate downstream signaling of insulin receptors.
Defects in the FRS2 protein can lead to the development of pathopathologies such as insulin resistance, obesity, bone metabolism disorders, and neurodegenerative diseases.
Customer Reviews (3)
Write a reviewThe catalytic activity of FRS2 is very powerful and can effectively accelerate the process of chemical reactions, which brings great convenience to our experiments.
Stability of FRS2 is very high, and it can maintain stable performance even in extreme environments, which shows its excellent adaptability and reliability.
The production process of FRS2 uses advanced biotechnology, which makes the production process more efficient and environmentally friendly, bringing a positive impact on the environment.
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