Recombinant Human FST Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FST-2557H
• Product Overview: FST MS Standard C13 and N15-labeled recombinant protein (NP_037541) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 38 kDa
• AA Sequence: MVRARHQPGGLCLLLLLLCQFMEDR SAQAGNCWLRQAKNGRCQVLYKTEL SKEECCSTGRLSTSWTEEDVNDNTL FKWMIFNGGAPNCIPCKETCENVDC GPGKKCRMNKKNKPRCVCAPDCSNI TWKGPVCGLDGKTYRNECALLKARC KEQPELEVQYQGRCKKTCRDVFCPG SSTCVVDQTNNAYCVTCNRICPEPA SSEQYLCGNDGVTYSSACHLRKATC LLGRSIGLAYEGKCIKAKSCEDIQC TGGKKCLWDFKVGRGRCSLCDELCP DSKSDEPVCASDNATYASECAMKEA ACSSGVLLEVKHSGSCNSISEDTEE EEEDEDQDYSFPISSILEWTRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FST follistatin [ Homo sapiens (human) ]
• Official Symbol: FST
• Synonyms: FST; follistatin; FS; activin-binding protein; follistatin isoform FST317
• Gene ID: 10468
• mRNA Refseq: NM_013409
• Protein Refseq: NP_037541
• MIM: 136470
• UniProt ID: P19883