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Recombinant Human FXN Protein, Myc/DDK-tagged, C13 and N15-labeled
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Cat.No. : | FXN-3162H |
Product Overview : | FXN MS Standard C13 and N15-labeled recombinant protein (NP_000135) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : | This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 23.1 kDa |
AA Sequence : | MWTLGRRAVA GLLASPSPAQ AQTLTRVPRP AELAPLCGRR GLRTDIDATC TPRRASSNQR GLNQIWNVKK QSVYLMNLRK SGTLGHPGSL DETTYERLAE ETLDSLAEFF EDLADKPYTF EDYDVSFGSG VLTVKLGGDL GTYVINKQTP NKQIWLSSPS SGPKRYDWTG KNWVYSHDGV SLHELLAAEL TKALKTKLDL SSLAYSGKDA TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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Gene Name : | FXN frataxin [ Homo sapiens (human) ] |
Official Symbol : | FXN |
Synonyms : | FXN; frataxin; FRDA, Friedreich ataxia; frataxin, mitochondrial; CyaY; FA; FARR; X25; Friedreich ataxia protein; FRDA; MGC57199; |
Gene ID : | 2395 |
mRNA Refseq : | NM_000144 |
Protein Refseq : | NP_000135 |
MIM : | 606829 |
UniProt ID : | Q16595 |
◆ Recombinant Protein
Fxn-3112M | Recombinant Mouse Fxn Protein, Myc/DDK-tagged | +Inquiry |
FXN-1060M | Recombinant Cynomolgus Monkey FXN Protein (81-210 aa), His-tagged | +Inquiry |
FXN-1397M | Recombinant Mouse FXN Protein (78-207 aa), His-tagged | +Inquiry |
Fxn-1218R | Recombinant Rat Fxn Protein, His-tagged | +Inquiry |
FXN-4576H | Recombinant Human FXN Protein, GST-tagged | +Inquiry |
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◆ Lysates
FXN-6108HCL | Recombinant Human FXN 293 Cell Lysate | +Inquiry |
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