Recombinant Human FXN Protein, Myc/DDK-tagged, C13 and N15-labeled FXN-3162H

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Recombinant Human FXN Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. :	FXN-3162H
Product Overview :	FXN MS Standard C13 and N15-labeled recombinant protein (NP_000135) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	23.1 kDa
AA Sequence :	MWTLGRRAVA GLLASPSPAQ AQTLTRVPRP AELAPLCGRR GLRTDIDATC TPRRASSNQR GLNQIWNVKK QSVYLMNLRK SGTLGHPGSL DETTYERLAE ETLDSLAEFF EDLADKPYTF EDYDVSFGSG VLTVKLGGDL GTYVINKQTP NKQIWLSSPS SGPKRYDWTG KNWVYSHDGV SLHELLAAEL TKALKTKLDL SSLAYSGKDA TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	FXN frataxin [ Homo sapiens (human) ]
Official Symbol :	FXN
Synonyms :	FXN; frataxin; FRDA, Friedreich ataxia; frataxin, mitochondrial; CyaY; FA; FARR; X25; Friedreich ataxia protein; FRDA; MGC57199;
Gene ID :	2395
mRNA Refseq :	NM_000144
Protein Refseq :	NP_000135
MIM :	606829
UniProt ID :	Q16595