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Recombinant Human FZD8 Protein, GST-tagged

Cat.No. : FZD8-4600H
Product Overview : Human FZD8 partial ORF ( NP_114072, 72 a.a. - 161 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 35.64 kDa
AA Sequence : FWPLVEIQCSPDLKFFLCSMYTPIC LEDYKKPLPPCRSVCERAKAGCAPL MRQYGFAWPDRMRCDRLPEQGNPDT LCMDYNRTDLTTAAP
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : FZD8 frizzled family receptor 8 [ Homo sapiens ]
Official Symbol : FZD8
Synonyms : FZD8; frizzled family receptor 8; frizzled (Drosophila) homolog 8, frizzled 8, seven transmembrane spanning receptor, frizzled homolog 8 (Drosophila); frizzled-8; frizzled homolog 8; frizzled 8, seven transmembrane spanning receptor; FZ-8; hFZ8;
Gene ID : 8325
mRNA Refseq : NM_031866
Protein Refseq : NP_114072
MIM : 606146
UniProt ID : Q9H461

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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