Recombinant Human GABRB1 Protein, His-tagged

• Cat.No.: GABRB1-1548H
• Product Overview: Recombinant Human GABRB1 Protein (His26-Tyr245) with N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: His26-Tyr245
• Description: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29 kDa
  Accurate Molecular Mass: 33 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 [ Homo sapiens (human) ]
• Official Symbol: GABRB1
• Synonyms: GABRB1; gamma-aminobutyric acid (GABA) A receptor, beta 1; gamma-aminobutyric acid receptor subunit beta-1; GABA(A) receptor; beta 1; GABA(A) receptor, beta 1; GABA(A) receptor subunit beta-1
• Gene ID: 2560
• mRNA Refseq: NM_000812
• Protein Refseq: NP_000803
• MIM: 137190
• UniProt ID: P18505