Recombinant Human GALE Protein, His-tagged
Cat.No. : | GALE-151H |
Product Overview : | Recombinant Human GALE, transcript variant 1, fused with His tag at C-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 50mM Tris-HCl, 150mM NaCl, 2mM DTT, 1mM EDTA, pH 8.0. |
Molecular Mass : | 40.4 kDa |
Endotoxin : | < 0.1 EU per µg protein as determined by LAL test |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | GALE UDP-galactose-4-epimerase [ Homo sapiens ] |
Official Symbol : | GALE |
Synonyms : | GALE; UDP-galactose-4-epimerase; galactose 4 epimerase, UDP; UDP-glucose 4-epimerase; SDR1E1; short chain dehydrogenase/reductase family 1E; member 1; UDP glucose 4 epimerase; galactowaldenase; UDP-galactose 4-epimerase; UDP galactose-4-epimerase; galactose-4-epimerase, UDP-; short chain dehydrogenase/reductase family 1E, member 1; FLJ95174; FLJ97302; |
Gene ID : | 2582 |
mRNA Refseq : | NM_000403 |
Protein Refseq : | NP_000394 |
MIM : | 606953 |
UniProt ID : | Q14376 |
Products Types
◆ Recombinant Protein | ||
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GALE-2398H | Recombinant Human GALE Protein (Met1-Ala348), N-His tagged | +Inquiry |
GALE-731H | Recombinant Human UDP-galactose-4-epimerase, His-tagged | +Inquiry |
◆ Lysates | ||
GALE-6043HCL | Recombinant Human GALE 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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