| Description : |
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
N-6×His, GFP |
| Molecular Mass : |
~92 kDa |
| Protein Length : |
AA 47-559 |
| AA Sequence : |
VLEPVQKPHEGPGEMGKPVVIPKED QEKMKEMFKINQFNLMASEMIALNR SLPDVRLEGCKTKVYPDNLPTTSVV IVFHNEAWSTLLRTVHSVINRSPRH MIEEIVLVDDASERDFLKRPLESYV KKLKVPVHVIRMEQRSGLIRARLKG AAVSKGQVITFLDAHCECTVGWLEP LLARIKHDRRTVVCPIIDVISDDTF EYMAGSDMTYGGFNWKLNFRWYPVP QREMDRRKGDRTLPVRTPTMAGGLF SIDIDYFQEIGTYDAGMDIWGGENL EISFRIWQCGGTLEIVTCSHVGHVF RKATPYTFPGGTGQIINKNNRRLAE VWMDEFKNFFYIISPGVTKVDYGDI SSRVGLRHKLQCKPFSWYLENIYPD SQIPRHYFSLGEIRNVETNQCLDNM ARKENEKVGIFNCHGMGGNQVFSYT ANKEIRTDDLCLDVSKLNGPVTMLK CHHLKGNQLWEYDPVKLTLQHVNSN QCLDKATEEDSQVPSIRDCNGSRSQ QWLLRNVTLPEIF |
| Purity : |
>95%, by SDS-PAGE under reducing conditions and visualized by Coomassie Blue stain. |
| Stability : |
6 months if stored at -80 centigrade. Avoid repeated freeze thaws. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
Supplied as a 0.2 μm filtered solution in 20mM HEPES pH 7.0 and 100mM NaCl buffer, with 10% Glycerol. |
| Preservative : |
0.05 % NaN3 |
| Shipping : |
This product is shipped as 0.2μm filtered product on dry ice. |
