| Description : |
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
64 kDa |
| AA Sequence : |
MRKFAYCKVVLATSLIWVLLDMFLL LYFSECNKCDEKKERGLPAGDVLEP VQKPHEGPGEMGKPVVIPKEDQEKM KEMFKINQFNLMASEMIALNRSLPD VRLEGCKTKVYPDNLPTTSVVIVFH NEAWSTLLRTVHSVINRSPRHMIEE IVLVDDASERDFLKRPLESYVKKLK VPVHVIRMEQRSGLIRARLKGAAVS KGQVITFLDAHCECTVGWLEPLLAR IKHDRRTVVCPIIDVISDDTFEYMA GSDMTYGGFNWKLNFRWYPVPQREM DRRKGDRTLPVRTPTMAGGLFSIDR DYFQEIGTYDAGMDIWGGENLEISF RIWQCGGTLEIVTCSHVGHVFRKAT PYTFPGGTGQIINKNNRRLAEVWMD EFKNFFYIISPGVTKVDYGDISSRV GLRHKLQCKPFSWYLENIYPDSQIP RHYFSLGEIRNVETNQCLDNMARKE NEKVGIFNCHGMGGNQVFSYTANKE IRTDDLCLDVSKLNGPVTMLKCHHL KGNQLWEYDPVKLTLQHVNSNQCLD KATEEDSQVPSIRDCNGSRSQQWLL RNVTLPEIFTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
