Recombinant Human GATA3 protein, MYC/DDK-tagged


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Recombinant Human GATA3 protein, MYC/DDK-tagged

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Cat.No. : GATA3-2941H
Product Overview : Recombinant Human GATA3, transcript variant 2, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description : This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
Source : HEK293
Species : Human
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 47.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : GATA3 GATA binding protein 3 [ Homo sapiens ]
Official Symbol : GATA3
Synonyms : GATA3; GATA binding protein 3; trans-acting T-cell-specific transcription factor GATA-3; HDR; GATA-binding factor 3; HDRS; MGC2346; MGC5199; MGC5445;
Gene ID : 2625
mRNA Refseq : NM_001002295
Protein Refseq : NP_001002295
MIM : 131320
UniProt ID : P23771
Chromosome Location : 10p15
Pathway : Adipogenesis, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; Hemostasis, organism-specific biosystem; IL27-mediated signaling events, organism-specific biosystem;
Function : DNA binding; E-box binding; HMG box domain binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; core promoter proximal region sequence-specific DNA binding; core promoter sequence-specific DNA binding; metal ion binding; nucleic acid binding transcription factor activity; nucleic acid binding transcription factor activity; protein binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription factor binding; transcription regulatory region DNA binding; transcription regulatory region sequence-specific DNA binding; zinc ion binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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