Recombinant Human GATM Protein, GST-tagged

• Cat.No.: GATM-4761H
• Product Overview: Human GATM full-length ORF ( NP_001473.1, 1 a.a. - 423 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 74.9 kDa
• AA Sequence: MLRVRCLRGGSRGAEAVHYIGSRLG RTLTGWVQRTFQSTQAATASSRNSC AADDKATEPLPKDCPVSSYNEWDPL EEVIVGRAENACVPPFTIEVKANTY EKYWPFYQKQGGHYFPKDHLKKAVA EIEEMCNILKTEGVTVRRPDPIDWS LKYKTPDFESTGLYSAMPRDILIVV GNEIIEAPMAWRSRFFEYRAYRSII KDYFHRGAKWTTAPKPTMADELYNQ DYPIHSVEDRHKLAAQGKFVTTEFE PCFDAADFIRAGRDIFAQRSQVTNY LGIEWMRRHLAPDYRVHIISFKDPN PMHIDATFNIIGPGIVLSNPDRPCH QIDLFKKAGWTIITPPTPIIPDDHP LWMSSKWLSMNVLMLDEKRVMVDAN EVPIQKMFEKLGITTIKVNIRNANS LGGGFHCWTCDVRRRGTLQSYLD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) [ Homo sapiens ]
• Official Symbol: GATM
• Synonyms: GATM; glycine amidinotransferase (L-arginine:glycine amidinotransferase); glycine amidinotransferase, mitochondrial; AGAT; transamidinase; L-arginine:glycine amidinotransferase; AT
• Gene ID: 2628
• mRNA Refseq: NM_001482
• Protein Refseq: NP_001473
• MIM: 602360
• UniProt ID: P50440