Recombinant Human GCKR Protein, MYC/DDK-tagged

• Cat.No.: GCKR-660H
• Product Overview: Recombinant Human GCKR fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 68.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: GCKR glucokinase (hexokinase 4) regulator [ Homo sapiens ]
• Official Symbol: GCKR
• Synonyms: GCKR; glucokinase (hexokinase 4) regulator; glucokinase (hexokinase 4) regulatory protein; glucokinase regulatory protein; GKRP; FGQTL5
• Gene ID: 2646
• mRNA Refseq: NM_001486
• Protein Refseq: NP_001477
• MIM: 600842
• UniProt ID: Q14397