Active Recombinant Human GDA Protein

• Cat.No.: GDA-354H
• Product Overview: Recombinant Human GDA Protein (1-454 aa) is produced by E. coli expression system.

Specification

• Description: GDA, also known as guanine deaminase, catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human GDA, was expressed in E. coli and purified by conventional chromatography techniques.
• Source: E. coli
• Species: Human
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT
• Bio-activity: Specific activity is > 2,000 pmol/min/ug, and is defined as the amount of enzyme that convert guanine to xanthine per minute at pH 8.0 at 37 centigrade.
• Molecular Mass: 51kDa (454 aa) confirmed by MALDI-TOF
• Protein length: 1-454 aa
• AA Sequence: MCAAQMPPLA HIFRGTFVHS TWTCPMEVLR DHLLGVSDSG KIVFLEEASQ QEKLAKEWCF KPCEIRELSH HEFFMPGLVD THIHASQYSF AGSSIDLPLL EWLTKYTFPA EHRFQNIDFA
  EEVYTRVVRR TLKNGTTTAC YFATIHTDSS LLLADITDKF GQRAFVGKVC MDLNDTFPEY KETTEESIKE TERFVSEMLQ KNYSRVKPIV TPRFSLSCSE TLMGELGNIA KTRDLHIQSH
  ISENRDEVEA VKNLYPSYKN YTSVYDKNNL LTNKTVMAHG CYLSAEELNV FHERGASIAH CPNSNLSLSS GFLNVLEVLK HEVKIGLGTD VAGGYSYSML DAIRRAVMVS NILLINKVNE
  KSLTLKEVFR LATLGGSQAL GLDGEIGNFE VGKEFDAILI NPKASDSPID LFYGDFFGDI SEAVIQKFLY LGDDRNIEEV YVGGKQVVPF SSSV
• Purity: > 90% by SDS - PAGE
• Applications: Enzyme Activity; SDS-PAGE
• Notes: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at +2 centigrade to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by absorbance at 280nm)

Gene Information

• Gene Name: GDA guanine deaminase [ Homo sapiens ]
• Official Symbol: GDA
• Synonyms: GDA; GAH; CYPIN; GUANASE; NEDASIN; MGC9982; KIAA1258
• Gene ID: 9615
• mRNA Refseq: NM_001242505
• Protein Refseq: NP_001229434
• MIM: 139260
• UniProt ID: Q9Y2T3